Project title: Green MIcrofluiDic PLAtform for advanced tissue on a Chip culturEs
Start/end date: october 2023 – november 2025
Funding Agency/Programme: Ministry of University and Research – PRIN (PROGETTI DI RICERCA DI RILEVANTE INTERESSE NAZIONALE/ RESEARCH PROJECTS OF RELEVANT NATIONAL INTEREST) – Call 2022
Partnership: Università degli Studi di Palermo (UO 1); Fondazione Ri.MED (Sub-UO of UO1); Politecnico di Torino (UO2); Politecnico di Milano (UO3); CNR Lecce (UO4).
Abstract: the GREEN-MID-PLACE project aims to develop an eco-sustainable Organ-on-Chip (OoC) platform for stem cell growth and differentiation. The focus is on utilizing bio-based polymers and environmentally friendly fabrication techniques. The OoC design involves a microfluidic platform optimized for human bone marrow mesenchymal stem cells (BMSC) and endothelial cells, using a biopolymeric scaffold. One of the primary goals of this project is to streamline production processes, conserve energy, and mitigate contamination concerns through the implementation of innovative deposition approaches. The leadership of the Prof. D’Amore’s group in designing the microfluidic platform through CFD analysis significantly enhances the potential of GREEN-MID-PLACE to propel advancements in biomedical research and treatment methodologies.
Ri.MED U.O.: Tissue Engineering Lab.
Ri.MED Principal Investigator: Antonio D’Amore
Ri.MED Leading Scientist: Federica Cosentino