Sala Mattarella, Palazzo Dei Normanni
Palermo, Italy
Statutory missions of the Foundation are the development of biotechnological and biomedical research approaches, aimed at transferring innovative therapies to patients, the dissemination of scientific knowledge and the training of highly qualified professionals in the Life Science sector.
Ri.MED translational research approaches are based on three main matrices: tissue engineering and bioengineering, drug discovery and immunotherapies and regenerative medicine.
Translational research is focused on the complementary integration of resources and skills of different matrices: basic research, preclinical research and development of new therapies, medical devices and biomarkers, and finally clinical trials. It is thanks to the commitment of the founding partners, especially the Italian National Research Council (CNR), the University of Pittsburgh and the University of Pittsburgh Medical Centre (UPMC), that the Foundation has been able to develop truly translational research programs and facilitate the training of young Italian biomedical scientists.
Thanks to the strategic partnership with the Palermo-based IRCCS ISMETT, Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, it has been possible to foster multidisciplinary projects in the field of regenerative medicine and cellular therapies including the creation of a GMP cell factory to support clinical trials. The goal of the Foundation is to facilitate the exchange of know-how between physicians and researchers, and translation for new discoveries and novel therapies from bench to bedside. The Foundation is also committed to the development of novel immunotherapies for the treatment of cancer and other diseases, and to limit rejection in patients receiving organ transplants.
Ri.MED now has a diversified and balanced project portfolio, led by a multidisciplinary team with clear milestones related to product development objectives from a bench to bedside perspective. The first Ri.MED Research Retreat therefore has been a moment of choral presentation of the activities and the reached goals, with an outlook for 2019.
Keynote speech
Angus Thomson, Ph.D., D.Sc.
Director of Transplant Immunology, Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine
Talks by Ri.MED Scientist
Chairman: Dario Vignali, Scientific Director, Fondazione Ri.MED
SESSION I
Gaetano Burriesci, PhD – Bioingegneering at Ri.MED
Antonio D’Amore, PhD – Cardiac tissue engineering program at RiMED: overview and opportunities for collaboration.
Salvatore Pasta, PhD – Computational Modeling and miRNA profiling for the Clinical Risk Stratification of Dilated Ascending Thoracic Aorta
Riccardo Gottardi, PhD – Loads, structure and signaling for cartilage regeneration
Paola Corti, PhD – Function of Globins in Heart Regeneration and Development
Maria Giovanna Francipane, PhD – Bioengineering a Kidney in Secondary Lymphoid Organs
SESSION II
Caterina Alfano, PhD – Molecular mechanisms of protein-misfolding diseases
Ugo Perricone, PhD – Ri.MED Computational Platform for Drug Design: Chemoinformatics and Molecular Modeling Approaches to Drug Discovery
Claudia Coronnello, PhD – Bioinformatics reaserch at Ri.MED. Focus on microRNA interactions network
Chiara Cipollina, PhD – The inflammasomes in cigarette smoke-induced chronic lung inflammation
Marco Fazzari, PhD – Esterification of electrophilic 10-nitro-oleic acid in systemic triglycerides limits michael addition and confers more favorable pharmacokinetics
Roberto Di Maio, PhD – Nox2/mitochondria interplay in Parkinson’s disease
SESSION III
Cinzia Chinnici, PhD – Mesenchymal stromal cell-derived secretome as a cell-free therapeutic option for Regenerative Medicine
Mariangela Pampalone – Cell Therapy: Human Amniotic Membrane-Derived Mesenchymal (hAMSCs) and Epithelial Stem cells (hAECs) for Regenerative Medicine
Bruno Douradinha, PhD – Crosstalk on M(E)D-R Crossroads: the Sicilian Klebs experience
Monica Miele, PhD – Development of an advanced therapy medicinal product to treat viral infection in transplanted patients
Ester Badami, PhD – The importance of being perfused
Sandra Cascio, PhD – Tissue-infiltrating macrophages modulate intestinal barrier function through sialylation of Mucin 1 in IBD and colitis-associated cancer
